If you use the same filename in different paths phpThumbOf will output the same file.
Resource 1:
Filepath original: img/resrouce-1/file.jpg
Filepath phpThumbOf: /assets/components/phpthumbof/cache/file.hash.jpg
Resource 2:
Filepath original: img/resrouce-2/file.jpg
Filepath phpThumbOf: /assets/components/phpthumbof/cache/file.hash.jpg
phpThumbOf uses the same file for both resources, because the path is not considered.