Use with postcss-modular-scale

[strarsis]

Quite often vertical-rhythm + modular-scale (postcss-modular-scale) is combined.

How can this be combined?
When this vertical rhythm processor uses the parent font-size as base for the rhythm,
will it also correctly switch between rhythms when the parent font-size changes by mediaquery?
I guess px-to-rem or px-to-em (with different parent font sizes) is necessary in that case to allow proper nesting?

:root {
  --ms-bases: 1, 0.75;
  --ms-ratios: 2;
}

.header {
  font-size: ms(4)rem;
}

In the example above taken from the postcss-modular-scale docs,
there would be a parent with base font-size, but not globally as not the html or body element is used.